4-Amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
4-Amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
CAS: 10212-20-1
Molecular Formula: C9H12FN3O4
4-Amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one - Names and Identifiers
| Name | 4-Amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one |
| Synonyms | 2'-FC 2'-FdC 2'-FLUORO-D-CYTIDINE 2'-FLUORO-2'-DEOXYCYTIDINE 2'-DEOXY-2'-FLUOROCYTIDINE 2'-Deoxy-2'-fluoro-D-cytidine 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)cytosine 4-amino-1-(2-deoxy-2-fluoropentofuranosyl)pyrimidin-2(1H)-one 2'-DEOXY-2'-FLUOROCYTIDINE(2'-FLUORO-2'- DEOXYCYTIDINE, 2'-FC) 4-amino-1-[(2r,3r,4r,5r)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one 4-Amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one 4-AMINO-1-((2R,3R,4R,5R)-3-FLUORO-4-HYDROXY-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-2-YL)-1H-PYRIMIDIN-2-ONE |
| CAS | 10212-20-1 |
| EINECS | 1806241-263-5 |
| InChI | InChI=1/C9H12FN3O4/c10-6-7(15)4(3-14)17-8(6)13-2-1-5(11)12-9(13)16/h1-2,4,6-8,14-15H,3H2,(H2,11,12,16)/t4-,6?,7-,8-/m1/s1 |
4-Amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one - Physico-chemical Properties
| Molecular Formula | C9H12FN3O4 |
| Molar Mass | 245.21 |
| Density | 1.82±0.1 g/cm3(Predicted) |
| Melting Point | 167 °C |
| Boling Point | 500.1±60.0 °C(Predicted) |
| Solubility | Soluble in DMSO, Methanol. |
| Appearance | Crystallization |
| Color | White to Off-white |
| pKa | 12.84±0.70(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,2-8°C |
| Refractive Index | 80 ° (C=1, MeOH) |
| MDL | MFCD04221217 |
| In vitro study | 2'-Deoxy-2'-fluorocytidine has antiviral activities, showing 50% effective concentrations (EC 50 ) of 61 nM and 31 nM against CCHFV and CCHFV/ZsG in Huh7 cells, respectively. And it shows a 50% cytotoxicity concentration (CC 50 ) of >50.0 μM in Huh7 cells. |
4-Amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| HS Code | 29389090 |
![4-Amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one](http://res.chembk.com/assets/images/structure/104572.jpg)
Supplier List
Spot supply
Product Name: 2-FDC Visit Supplier Webpage Request for quotationCAS: 10212-20-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Product Name: 2'-Fluoro-2'-Deoxycytidine Request for quotation
CAS: 10212-20-1
Tel: +86-571-88162785
Email: Lucy@verypharm.com
Mobile: +86-13606544505
QQ: 472954302
Product List: View Catalog
CAS: 10212-20-1
Tel: +86-571-88162785
Email: Lucy@verypharm.com
Mobile: +86-13606544505
QQ: 472954302
Product List: View Catalog
Spot supply
Product Name: 2-FDC Visit Supplier Webpage Request for quotationCAS: 10212-20-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Product Name: 2'-Fluoro-2'-Deoxycytidine Request for quotation
CAS: 10212-20-1
Tel: +86-571-88162785
Email: Lucy@verypharm.com
Mobile: +86-13606544505
QQ: 472954302
Product List: View Catalog
CAS: 10212-20-1
Tel: +86-571-88162785
Email: Lucy@verypharm.com
Mobile: +86-13606544505
QQ: 472954302
Product List: View Catalog
View History